LIX Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-345-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-345-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
The lyophilized LIX recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted LIX is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing
Documents
Further Information
Additional Names:
LIX, GCP-2, Scyb5, Scyb6, ENA-78, AMCF-II, C-X-C motif chemokine 5, Cytokine LIX
Background:
CXCL6, also known as GCP-2 in humans and LIX in mice, is a connective tissue-derived CXC chemokine that contains the four conserved cysteine residues shared by CXC chemokines and the ?ELR? motif responsible for CXCR1 and CXCR2 receptor signaling. Constitutively expressed in monocytes, platelets, endothelial cells and mast cells, CXCL6 selectively chemoattracts neutrophils and has been shown to exert anti-angiogenic activity. Human GCP-2 and murine LIX respectively exhibit murine and human cell cross-reactivity. There are two naturally occurring variants of murine LIX, the 78 amino-acid-length LIX 1-78 (GCP-2) and the 70 amino-acid-length LIX 9-78 (GCP-2).
Biological Activity:
Biological activity was determined by its ability to chemoattract human neutrophils using a concentration range of 10 - 100 ng/mL.
NCBI Gene ID #:
20311
NCBI Official Name:
chemokine (C-X-C motif) ligand 5
NCBI Official Symbol:
Cxcl5
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_033167.2
Protein GI Number:
114842398
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P50228