TRAIL Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-459-0.01mg | 0.01mg | £300.00 |
Quantity:
| PSI-40-459-0.05mg | 0.05mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
The lyophilized TRAIL recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TRAIL is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
Documents
Further Information
Additional Names:
TL2, Ly81, Trail, APO-2L, AI448571, A330042I21Rik, Tumor necrosis factor ligand superfamily member 10, TNF-related apoptosis-inducing ligand, Protein TRAIL
Background:
TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain?, which activates the cell?s apoptotic machinery. Recombinant murine soluble TRAIL is a 174 amino acid polypeptide (20.0 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL protein.
Biological Activity:
Biological activity was determined by the dose - dependent stimulation of MIP - 2 production by mouse spleen cells using a concentration range of 10 - 100 ng/mL.
NCBI Gene ID #:
22035
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 10
NCBI Official Symbol:
Tnfsf10
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_033451.1
Protein GI Number:
6678431
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P50592