VEGF165 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-482-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-482-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Rat
Storage:
The lyophilized VEGF165 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted VEGF165 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, e
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Further Information
Additional Names:
VPF, Vegf, VEGF-A, VEGF164, Vascular endothelial growth factor A, Vascular permeability factor
Background:
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase(flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant rat VEGF is a 38.5 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Biological Activity:
Biological activity was determined by the dose - dependent stimulation of the proliferation of Human umbilical vein endothelial cells (HUVEC). The expected ED50 is 4.0 - 8.0 ng/mL.
NCBI Gene ID #:
83785
NCBI Official Name:
vascular endothelial growth factor A
NCBI Official Symbol:
Vegfa
NCBI Organism:
Rattus norvegicus
Physical State:
Lyophilized
Protein Accession #:
NP_001103803.1
Protein GI Number:
160358793
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P16612-2