CD73 Antibody [AD2] (APC)
| Code | Size | Price |
|---|
| PSI-76-311-100tests | 100tests | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: AD2
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
NT, eN, NT5, NTE, eNT, CD73, E5NT, CALJA, NT5E
Background:
The AD2 monoclonal antibody specifically reacts with human CD73 (ecto-5?-nucleotidase), a 70 kDA glycosyl phosphatidylinositol (GPI)-anchored glycoprotein. CD73 catalyzes the dephosphorylation of adenosine monophosphate (AMP) to adenosine and is expressed on subsets of B, T, dendritic, endothelial, and mesenchymal stem cells. It is also involved in the adhesion of lymphocytes to endothelium and T cell activation.
Background References:
- Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
- Nakamura, T., Kubagawa, H., Ohno, T., Cooper, M. D. (1993). Characterization of an IgM Fc-binding receptor on human T cells.The Journal of Immunology,151(12), 6933-6941.
- Alam, M. S., Kurtz, C. C., Rowlett, R. M., Reuter, B. K., Wiznerowicz, E., Das, S., ... Ernst, P. B. (2009). CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice.Journal of Infectious Diseases,199(4), 494-504.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
APC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
4907
NCBI Official Name:
5'-nucleotidase, ecto (CD73)
NCBI Official Symbol:
NT5E
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology
SPECIFICITY:
The AD2 monoclonal antibody specifically reacts with human CD73 (ecto-5?-nucleotidase), a 70 kDA glycosyl phosphatidylinositol (GPI)-anchored glycoprotein.
Swissprot #:
P21589
User NOte:
Optimal dilutions for each application to be determined by the researcher.