CD38 Antibody [HIT2] (APC)
| Code | Size | Price |
|---|
| PSI-76-752-100tests | 100tests | £536.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: HIT2
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
T10, ADPRC 1, CD38
Background:
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, macrophages, dendritic cells, and thymocytes. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
Background References:
- Oliver, A. M., Martin, F., Kearney, J. F. (1997). Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells.The Journal of Immunology,158(3), 1108-1115.
- Bean, A. G., Godfrey, D. I., Ferlin, W. G., Santos-Argumedo, L., Parkhouse, R. M. E., Howard, M. C., Zlotnik, A. (1995). CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of alpha -beta TCR+ CD4 CD8 thymocytes.International immunology,7(2), 213-221.
- Lund, F., Solvason, N., Grimaldi, J. C., Michael, R., Parkhouse, E., Howard, M. (1995). Murine CD38: an immunoregulatory ectoenzyme.Immunology today,16(10), 469-473.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
APC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
952
NCBI Official Name:
CD38 molecule
NCBI Official Symbol:
CD38
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Stem Cell
SPECIFICITY:
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein.
Swissprot #:
P28907
User NOte:
Optimal dilutions for each application to be determined by the researcher.