CD15 Antibody [HI98] (APC)
| Code | Size | Price |
|---|
| PSI-76-497-100tests | 100tests | £633.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgM, kappa
Antibody Clonality: Monoclonal
Antibody Clone: HI98
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
LeX, CD15, ELFT, FCT3A, FUTIV, SSEA-1, FUC-TIV, FUT4
Background:
The HI98 monoclonal antibody specifically reacts with CD15, a 220 kDa carbohydrate moiety also known as SSEA-1, Lewis 3-fucosyl-N-acetyllactosamine (3-FAL). CD15 is expressed on most granulocytes and monocytes to the exclusion of lymphocytes and basophils. It is involved in cell adhesion, chemotaxis, and phagocytosis.
Background References:
- Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
- Barclay, A. N., Brown, M. H., Law, S. A. K. A., McKnight, A. J., Tomlinson, M. G., van der Merwe, P. A. (1997).The leucocyte antigen factsbook. Academic Press.
- Lund-Johansen, F., Olweus, J., Horejsi, V., Skubitz, K. M., Thompson, J. S., Vilella, R., Symington, F. W. (1992). Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65).Journal of immunology (Baltimore, Md.: 1950),148(10), 3221.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
APC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
2526
NCBI Official Name:
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
NCBI Official Symbol:
FUT4
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity,Stem Cell
SPECIFICITY:
The HI98 monoclonal antibody specifically reacts with CD15, a 220 kDa carbohydrate moiety also known as SSEA-1, Lewis 3-fucosyl-N-acetyllactosamine (3-FAL).
Swissprot #:
P22083
User NOte:
Optimal dilutions for each application to be determined by the researcher.