CD272 Antibody [MIH26] (Biotin)
| Code | Size | Price |
|---|
| PSI-76-945-0.025mg | 0.025mg | £404.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: MIH26
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
BTLA1, CD272, BTLA
Background:
The MIH26 monoclonal antibody specifically reacts with human CD272, the human and B and T lymphocyte attenuator (BTLA). It is expressed on macrophage, dendritic, NK, NKT, B, and T cells. CD272 (BTLA) is an inhibitory receptor that inhibits T cell proliferation after binding with its ligand, the herpes virus entry mediator (HVEM). It is in the CD28-like family of receptors and is structurally similar to CTLA-4 and PD-1.
Background References:
- Flo, T. H., Halaas, ., Lien, E., Ryan, L., Teti, G., Golenbock, D. T., ... Espevik, T. (2000). Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.The Journal of Immunology,164(4), 2064-2069.
- Lien, E., Sellati, T. J., Yoshimura, A., Flo, T. H., Rawadi, G., Finberg, R. W., ... Golenbock, D. T. (1999). Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.Journal of Biological Chemistry,274(47), 33419-33425.
- Cook, E. B., Stahl, J. L., Esnault, S., Barney, N. P., Graziano, F. M. (2005). Toll-like receptor 2 expression on human conjunctival epithelial cells: a pathway for
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
Biotin
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
151888
NCBI Official Name:
B and T lymphocyte associated
NCBI Official Symbol:
BTLA
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology
SPECIFICITY:
The MIH26 monoclonal antibody specifically reacts with human CD272, the human and B and T lymphocyte attenuator (BTLA).
Swissprot #:
Q7Z6A9
User NOte:
Optimal dilutions for each application to be determined by the researcher.