IFN gamma Antibody [4S.B3] (FITC)

ProSci
Product Code: PSI-77-031
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-77-031-25tests25tests£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 4S.B3
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Further Information

Additional Names:
IFG, IFI, IFNG
Background:
The 4S.B3 is a neutralizing antibody that binds with the human Interferon-gamma (IFN-gamma) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
3458
NCBI Official Name:
interferon, gamma
NCBI Official Symbol:
IFNG
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity,Immunology,Chemokines & Cytokines, Growth Factors
SPECIFICITY:
The 4S.B3 is a neutralizing antibody that binds with the human Interferon-gamma (IFN-gamma) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties.
Swissprot #:
P01579
User NOte:
Optimal dilutions for each application to be determined by the researcher.