CD19 Antibody [HIB19] (FITC)
| Code | Size | Price |
|---|
| PSI-76-788-100tests | 100tests | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: HIB19
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
B4, CVID3, CD19
Background:
The HIB19 monoclonal antibody specifically reacts with human CD19, a 95kDA type 1 transmembrane glycoprotein also known as B4. It is expressed on all stages of B cell development except for final plasma cells and on follicular dendritic cells. CD19 plays a role in B cell proliferation, activation, and differentiation. It functions as a BCR co-receptor with CD21 and CD81.
Background References:
- Hemler, M. E., Sanchez-Madrid, F., Flotte, T. J., Krensky, A. M., Burakoff, S. J., Bhan, A. K., ... Strominger, J. L. (1984). Glycoproteins of 210,000 and 130,000 mw on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines.The Journal of Immunology,132(6), 3011-3018.
- Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
- Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., Springer, T. A. (1982). Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.Proceedings of the National Academy of Sciences,79(23), 7489-7493.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
930
NCBI Official Name:
CD19 molecule
NCBI Official Symbol:
CD19
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology
SPECIFICITY:
The HIB19 monoclonal antibody specifically reacts with human CD19, a 95kDA type 1 transmembrane glycoprotein also known as B4.
Swissprot #:
P15391
User NOte:
Optimal dilutions for each application to be determined by the researcher.