CD33 Antibody [WM53] (FITC)
| Code | Size | Price |
|---|
| PSI-76-309-100tests | 100tests | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: WM53
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
p67, SIGLEC3, SIGLEC-3, CD33
Background:
The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67. CD33 is expressed on monocytes, granulocytes, dendritic cells, mast cells, and myeloid progenitors to the exclusion of hematopoietic stem cells, lymphocytes, and platelets. It functions to assist sialic acid-dependent cell adhesion.
Background References:
- Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
- Favaloro, E. J., Bradstock, K. F., Kabral, A., Grimsley, P., Zowtyj, H., Zola, H. (1988). Further characterization of human myeloid antigens (gp160, 95; gp150; gp67): investigation of epitopic heterogeneity and nonhaemopoietic distribution using panels of monoclonal antibodies belonging to CD11b, CD13 and CD33.British journal of haematology,69(2), 163-171
- Freeman, S. D., Kelm, S., Barber, E. K., Crocker, P. R. (1995). Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.Blood,85(8), 2005-2012.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
945
NCBI Official Name:
CD33 molecule
NCBI Official Symbol:
CD33
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
SPECIFICITY:
The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67.
Swissprot #:
P20138
User NOte:
Optimal dilutions for each application to be determined by the researcher.