CD11c Antibody [3.9] (PE)
| Code | Size | Price |
|---|
| PSI-76-146-100tests | 100tests | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 3.9
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
CD11C, SLEB6, ITGAX
Background:
The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin alpha chain also known as integrin alpha X. It is expressed on macrophages, granulocytes, monocytes, dendritic cells, natural killer cells, and subsets of B and T lymphocytes. The CD11c/CD18 complex associates with the iC3b, fibrinogen and ICAM-1 and has an important function in leukocyte adhesion.
Background References:
- Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
- Knapp W(1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
- McMichael, A. J. (1987). Leucocyte typing III.Oxford University Press, Oxford. Norton AJ, Isaacson PG (1985)
- Ottonello, L., Epstein, A. L., Dapino, P., Barbera, P., Morone, P., Dallegri, F. (1999). Monoclonal Lym-1 antibody-dependent cytolysis by neutrophils exposed to granulocyte-macrophage colony-stimulating factor: intervention of Fc-gamma RII (CD32), CD11b-CD18 integrins, and CD66b glycoproteins.Blood,93(10), 3505-3511.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
3687
NCBI Official Name:
integrin, alpha X (complement component 3 receptor 4 subunit)
NCBI Official Symbol:
ITGAX
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity
SPECIFICITY:
The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin alpha chain also known as integrin alpha X.
Swissprot #:
P20702
User NOte:
Optimal dilutions for each application to be determined by the researcher.