CD123 Antibody [6H6] (PE)
| Code | Size | Price |
|---|
| PSI-76-857-100tests | 100tests | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 6H6
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
IL3R, CD123, IL3RX, IL3RY, IL3RAY, hIL-3Ra, IL3RA
Background:
The 6H6 monoclonal antibody specifically reacts with human CD123, the alpha chain subunit of the IL-3 receptor. CD123?s affinity to IL-3 is low, but increases when associated with CD131. It can be found on basophils, dendritic cells, macrophages, and mast cells.
Background References:
- Agrawal, L., Maxwell, C. R., Peters, P. J., Clapham, P. R., Liu, S. M., Mackay, C. R., Strayer, D. S. (2009). Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia.Journal of General Virology,90(3), 710-722.
- Heath, H., Qin, S., Rao, P., Wu, L., LaRosa, G., Kassam, N., ... Mackay, C. R. (1997). Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody.Journal of Clinical Investigation,99(2), 178.
- Choe, H., Farzan, M., Sun, Y., Sullivan, N., Rollins, B., Ponath, P. D., ... Sodroski, J. (1996). The -beta--chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates.Cell,85(7), 1135-1148.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
3563
NCBI Official Name:
interleukin 3 receptor, alpha (low affinity)
NCBI Official Symbol:
IL3RA
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Stem Cell,Chemokines & Cytokines, Growth Factors
SPECIFICITY:
The 6H6 monoclonal antibody specifically reacts with human CD123, the alpha chain subunit of the IL-3 receptor.
Swissprot #:
P26951
User NOte:
Optimal dilutions for each application to be determined by the researcher.