CD25 Antibody [BC96] (PE)
| Code | Size | Price |
|---|
| PSI-76-500-100tests | 100tests | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: BC96
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
p55, CD25, IL2R, TCGFR, IDDM10, IL2RA
Background:
The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor alpha (IL-2R alpha, also known as CD25). CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor beta chain (CD122) and the common gamma chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.
Background References:
- Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York
- Zhang, B., Zhang, X., Tang, F. L., Zhu, L. P., Liu, Y., Lipsky, P. E. (2008). Clinical significance of increased CD4+ CD25 Foxp3+ T cells in patients with new-onset systemic lupus erythematosus.Annals of the rheumatic diseases,67(7), 1037-1040.
- Chapel, A., Bensussan, A., Vilmer, E., Dormont, D. (1992). Differential human immunodeficiency virus expression in CD4+ cloned lymphocytes: from viral latency to replication.Journal of virology,66(6), 3966-3970.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
3559
NCBI Official Name:
interleukin 2 receptor, alpha
NCBI Official Symbol:
IL2RA
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology
SPECIFICITY:
The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor alpha (IL-2R alpha, also known as CD25).
Swissprot #:
P01589
User NOte:
Optimal dilutions for each application to be determined by the researcher.