CD69 Antibody [FN50] (PE)
| Code | Size | Price |
|---|
| PSI-76-816-25tests | 25tests | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: FN50
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
AIM, EA1, MLR-3, CLEC2C, GP32/28, BL-AC/P26, CD69
Background:
The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
Background References:
- Marzio, R., Jirillo, E., Ransijn, A., Mauel, J., Corradin, S. B. (1997). Expression and function of the early activation antigen CD69 in murine macrophages.Journal of leukocyte biology,62(3), 349-355.
- Yokoyama, W. M., Koning, F., Kehn, P. J., Pereira, G. M., Stingl, G., Coligan, J. E., Shevach, E. M. (1988). Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation.The Journal of Immunology,141(2), 369-376.
- Sobel, E. S., Yokoyama, W. M., Shevach, E. M., Eisenberg, R. A., Cohen, P. L. (1993). Aberrant expression of the very early activation antigen on MRL/Mp-lpr/lpr lymphocytes.The Journal of Immunology,150(2), 673-682.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
969
NCBI Official Name:
CD69 molecule
NCBI Official Symbol:
CD69
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology
SPECIFICITY:
The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM).
Swissprot #:
Q07108
User NOte:
Optimal dilutions for each application to be determined by the researcher.