CD5 Antibody [UCHT2] (PE)

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ProSci
Product Code: PSI-76-611
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-76-611-100tests100tests£433.00
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Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: UCHT2
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Images

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Human peripheral blood lymphocytes were stained with PE UCHT2 with relevant isotype control in Red.
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Human peripheral blood lymphocytes were stained with PE UCHT2 with relevant isotype control in Red.

Documents

Further Information

Additional Names:
T1, LEU1, CD5
Background:
The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein. CD5 is expressed on mature T cells, a subset of B cells, and peripheral blood dendritic cells. B cells that are CD5+ produce mostly IgM polyreactive antibodies. Its ligand is CD72, which is involved in T, B cell proliferation and interaction. The UCT2 antibody also recognizes non-human primate CD5.
Background References:
  • McMichael, A. J. (1987).Leucocyte typing III: white cell differentiation antigens. Oxford University Press, USA.
  • Lankester, A. C., van Schijndel, G. M., Cordell, J. L., van Noesel, C. J., van Lier, R. A. (1994). CD5 is associated with the human B cell antigen receptor complex.European journal of immunology,24(4), 812-816.
  • Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., ... A't Hart, B. (2009). A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.Journal of Histochemistry Cytochemistry,57(12), 1159-1167.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
921
NCBI Official Name:
CD5 molecule
NCBI Official Symbol:
CD5
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology
SPECIFICITY:
The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein.
Swissprot #:
P06127
User NOte:
Optimal dilutions for each application to be determined by the researcher.