CD48 Antibody [156-4H9]
| Code | Size | Price |
|---|
| PSI-76-757-0.5mg | 0.5mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 156-4H9
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Functional Study
Storage:
The product should be stored undiluted at 4°C. Do not freeze.
Documents
Further Information
Additional Names:
BCM1, BLAST, hCD48, mCD48, BLAST1, SLAMF2, MEM-102, CD48
Background:
The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells and its expression increases in B cells upon activation.
Background References:
- Kato, K., Koyanagi, M., Okada, H., Takanashi, T., Wong, Y. W., Williams, A. F., ... Yagita, H. (1992). CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.The Journal of experimental medicine,176(5), 1241-1249.
- Qin, L., Chavin, K. D., Lin, J., Yagita, H., Bromberg, J. S. (1994). Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival.The Journal of experimental medicine,179(1), 341-346.
- Chavin, K. D., Qin, L., Lin, J., Woodward, J., Baliga, P., Kato, K., ... Bromberg, J. S. (1994). Anti-CD48 (murine CD2 ligand) mAbs suppress cell mediated immunity in vivo.International immunology,6(5), 701-709.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
962
NCBI Official Name:
CD48 molecule
NCBI Official Symbol:
CD48
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Innate Immunity,Immunology,Stem Cell
SPECIFICITY:
The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily.
Swissprot #:
P09326
User NOte:
Optimal dilutions for each application to be determined by the researcher.