CD11a Antibody [HI111]

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ProSci
Product Code: PSI-76-152
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-76-152-0.05mg0.05mg£404.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: HI111
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Functional Study
Storage:
The product should be stored undiluted at 4°C. Do not freeze.

Documents

Further Information

Additional Names:
CD11A, LFA-1, LFA1A, ITGAL
Background:
The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The heterodimer can bind to CD50 (ICAM-3), CD54 (ICAM-1), and CD102 (ICAM-2).
Background References:
  • Inghirami, G., Wieczorek, R., Zhu, B. Y., Silber, R., Dalla-Favera, R., Knowles, D. M. (1988). Differential expression of LFA-1 molecules in non-Hodgkin's lymphoma and lymphoid leukemia.Blood,72(4), 1431-1434.
  • Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
  • Bochner, B. S., Luscinskas, F. W., Gimbrone, M. A., Newman, W., Sterbinsky, S. A., Derse-Anthony, C. P., ... Schleimer, R. P. (1991). Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules.The Journal of experimental medicine,173(6), 1553-1557.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
3683
NCBI Official Name:
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
NCBI Official Symbol:
ITGAL
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Cancer,Functional Assays
SPECIFICITY:
The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein.
Swissprot #:
P20701
User NOte:
Optimal dilutions for each application to be determined by the researcher.