CD66b Antibody [G10F5]

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ProSci
Product Code: PSI-76-590
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-76-590-0.1mg0.1mg£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgM, kappa
Antibody Clonality: Monoclonal
Antibody Clone: G10F5
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Immunohistochemistry (IHC)
Storage:
The product should be stored undiluted at 4°C. Do not freeze.

Documents

Further Information

Additional Names:
CD67, CGM6, CD66b, NCA-95, CEACAM8
Background:
The G10F5 monoclonal antibody specifically reacts with human CD66b, a 100kDa glycosylphosphatidylinositol (GPI) linked protein in the granulocyte-specific activation family. CD66b is expressed on granulocytes, neutrophils, and eosinophils. It is reported that this molecule plays a role in regulating neutrophil activation and cellular adhesion. It was previously classified as CD67, but renamed CD66b in the Fifth HLDA Workshop.
Background References:
  • Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
  • Lund-Johansen, F. R. I. D. T. J. O. F., Olweus, J. O. H. A. N. N. A., Horejsi, V. A. C. L. A. V., Skubitz, K. M., Thompson, J. S., Vilella, R., Symington, F. W. (1992). Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65).The Journal of Immunology,148(10), 3221-3229.
  • Schmidt, T., Zndorf, J., Grger, T., Brandenburg, K., Reiners, A. L., Zinserling, J., Schnitzler, N. (2012). CD66b overexpression and homotypic aggregation of human peripheral blood neutrophils after activation by a gram-positive stimulus.Journal of leukocyte biology,91(5), 791-802.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
1088
NCBI Official Name:
carcinoembryonic antigen-related cell adhesion molecule 8
NCBI Official Symbol:
CEACAM8
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography.
Research Area:
Innate Immunity
SPECIFICITY:
The G10F5 monoclonal antibody specifically reacts with human CD66b, a 100kDa glycosylphosphatidylinositol (GPI) linked protein in the granulocyte-specific activation family.
Swissprot #:
P31997
User NOte:
Optimal dilutions for each application to be determined by the researcher.