CD19 Antibody [HIB19] (Violet-450)
| Code | Size | Price |
|---|
| PSI-76-761-100tests | 100tests | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: HIB19
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
B4, CVID3, CD19
Background:
The HIB19 monoclonal antibody reacts with a human 95 kDa transmembrane glycoprotein known as CD19, which is expressed by B lymphocytes during all the developmental stages, except for the terminally differentiated plasma cells. CD19 is also expressed on follicular dendritic cells, and seems to ensure the regulation of B lymphocytes proliferation. CD19, CD21, CD81, MHC class II, and Leu13 can bind together and form a complex which associates with the B cell receptor (BCR) on the surface of B lymphocytes and facilitates the signal transduction.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.
Background References:
- Knapp W(1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
- Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York
- McMichael, A. J., Beverley, P. C. L., Cobbold, S., Crumpton, M. J., Gilks, W., Gotch, F. M., ... Waldman, H. (1987). Leukocyte typing III.White Cell Differentiation Antigens, 733-786.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
Violet-450
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
930
NCBI Official Name:
CD19 molecule
NCBI Official Symbol:
CD19
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology
SPECIFICITY:
The HIB19 monoclonal antibody reacts with a human 95 kDa transmembrane glycoprotein known as CD19, which is expressed by B lymphocytes during all the developmental stages, except for the terminally differentiated plasma cells.
Swissprot #:
P15391
User NOte:
Optimal dilutions for each application to be determined by the researcher.