CD27 Antibody [O323] (Violet-450)
| Code | Size | Price |
|---|
| PSI-76-619-25tests | 25tests | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: O323
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Documents
Further Information
Additional Names:
T14, S152, Tp55, TNFRSF7, S152. LPFS2, CD27
Background:
The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells. CD27 is upregulated by T lymphocytes stimulation, and binds to CD70, enhancing the interaction between T and B lymphocytes. CD27 is a marker of memory B cells.
Background References:
- Knapp W(1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
- Correia, D. V., Fogli, M., Hudspeth, K., da Silva, M. G., Mavilio, D., Silva-Santos, B. (2011). Differentiation of human peripheral blood Vdelta-1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells.Blood,118(4), 992-1001.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
Violet-450
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
939
NCBI Official Name:
CD27 molecule
NCBI Official Symbol:
CD27
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology,Apoptosis
SPECIFICITY:
The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells.
Swissprot #:
P26842
User NOte:
Optimal dilutions for each application to be determined by the researcher.