MYT1 (phospho Ser83) Antibody
| Code | Size | Price |
|---|
| PSI-79-858-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
PMYT1, PKMYT1, MYT1 kinase
Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Background References:
- Booher R.N., J. Biol. Chem. 272:22300-22306(1997).
- Liu F., Mol. Cell. Biol. 17:571-583(1997).
- Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MYT1 (phospho Ser83) antibody was raised against a peptide sequence around phosphorylation site of Serine 83 (R-V-S (p)-F-R) derived from Human MYT1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
9088
NCBI Official Name:
protein kinase, membrane associated tyrosine/threonine 1
NCBI Official Symbol:
PKMYT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
XP_006721039.1
Protein GI Number:
33383241
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of MYT1 only when phosphorylated at serine 83.
Swissprot #:
Q99640