CDC25C (phospho Ser198) Antibody
| Code | Size | Price |
|---|
| PSI-79-900-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
CDC25M1, MPI1B, MPIP3, EC 3.1.3.48
Background:
cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded
protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Background References:
- Sadhu K., Proc. Natl. Acad. Sci. U.S.A. 87:5139-5143(1990).
- Bureik M., Int. J. Oncol. 17:1251-1258(2000).
- Wegener S., Eur. J. Cell Biol. 79:810-815(2000).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CDC25C (phospho Ser198) antibody was raised against a peptide sequence around phosphorylation site of Serine 198 (E-F-S (p)-L-K) derived from Human CDC25C.
Modifications:
Phospho-Specific
NCBI Gene ID #:
995
NCBI Official Name:
cell division cycle 25C
NCBI Official Symbol:
CDC25C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
NP_001274511.1
Protein GI Number:
12408658
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of CDC25C only when phosphorylated at serine 198.
Swissprot #:
P30307