MDC1 (phospho Ser513) Antibody
| Code | Size | Price |
|---|
| PSI-79-916-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
IER3, NFBD1, KIAA0170, DKFZp781A0122
Background:
The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.
Background References:
- Nagase T., DNA Res. 3:17-24(1996).
- Shiina T., Genetics 173:1555-1570(2006).
- Mungall A.J., Nature 425:805-811(2003).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MDC1 (phospho Ser513) antibody was raised against a peptide sequence around phosphorylation site of Serine 513 (E-R-S (p)-Q-A) derived from Human MDC1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
9656
NCBI Official Name:
mediator of DNA-damage checkpoint 1
NCBI Official Symbol:
MDC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
226 kDa
Protein Accession #:
NP_055456.2
Protein GI Number:
132626688
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of MDC1 only when phosphorylated at serine 513.
Swissprot #:
Q14676