CCR5 (phospho Ser349) Antibody
| Code | Size | Price |
|---|
| PSI-79-782-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
C-C CKR-5, CKR5, CHEMR13, CMKBR5, CCR-5
Application Note:
Western Blot: 1:500~1:1000
Background:
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
Background References:
- Martin Oppermann, J. Biol. Chem., Mar 1999; 274: 8875.
- Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003; 278: 2190 - 2198.
- Ramtin Rahbar, J. Virol., Jul 2006; 80: 7245 - 7259.
- H Olbrich, J. Leukoc. Biol., Mar 1999; 65: 281.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CCR5 (phospho Ser349) antibody was raised against a peptide sequence around phosphorylation site of Serine 349 (E-I-S (p)-V-G) derived from Human CCR5.
Modifications:
Phospho-Specific
NCBI Gene ID #:
1234/727797
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
NP_000570.1
Protein GI Number:
4502639
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of CCR5 only when phosphorylated at serine 349.
Swissprot #:
P51681