CD32 (phospho Tyr292) Antibody
| Code | Size | Price |
|---|
| PSI-79-796-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
CD32, FCG2, FCG2B,, LY-17, CDW32
Application Note:
Western Blot: 1:500~1:1000
Background:
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Background References:
- Stuart S.G., EMBO J. 8:3657-3666(1989).
- Brooks D.G., J. Exp. Med. 170:1369-1385(1989).
- Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CD32 (phospho Tyr292) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y (p)-S-L) derived from Human CD32.
Modifications:
Phospho-Specific
NCBI Gene ID #:
2213
NCBI Official Name:
Fc fragment of IgG, low affinity IIb, receptor (CD32)
NCBI Official Symbol:
FCGR2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
NP_003992.3
Protein GI Number:
50511930
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of CD32 only when phosphorylated at tyrosine 292.
Swissprot #:
P31994