Neutrophil Cytosol Factor 1 (phospho Ser304) Antibody

ProSci
Product Code: PSI-79-821
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-821-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

1 / 1
Western blot analysis of extracts from JK cells (Lane 2) and cos-7 cells (Lane 3), using Neutrophil Cytosol Factor 1 (Phospho-Ser304) Antibody. The lane on the left is treated with antigen-specific peptide.

Western blot analysis of extracts from JK cells (Lane 2) and cos-7 cells (Lane 3), using Neutrophil Cytosol Factor 1 (Phospho-Ser304) Antibody. The lane on the left is treated with antigen-specific peptide.

Further Information

Additional Names:
NCF1, NCF-47K, P47 phox
Application Note:
Western Blot: 1:500~1:1000
Background:
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Background References:
  • Rodaway A.R.F., Mol. Cell. Biol. 10:5388-5396(1990).
  • Gorlach A., J. Clin. Invest. 100:1907-1918(1997).
  • Chanock S.J., Blood Cells Mol. Dis. 26:37-46(2000)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Neutrophil Cytosol Factor 1 (phospho Ser304) antibody was raised against a peptide sequence around phosphorylation site of Serine 304 (R-S-S (p)-I-R) derived from Human Neutrophil Cytosol Factor 1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
653361
NCBI Official Name:
neutrophil cytosolic factor 1
NCBI Official Symbol:
NCF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
NP_000256.4
Protein GI Number:
115298672
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Neutrophil Cytosol Factor 1 only when phosphorylated at serine 304.
Swissprot #:
P14598