Caveolin 2 (phospho Tyr27) Antibody
| Code | Size | Price |
|---|
| PSI-79-888-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
CAV2, Caveolin-2
Application Note:
Western Blot: 1:500~1:1000
Background:
The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.
Background References:
- Scherer P.E., Proc. Natl. Acad. Sci. U.S.A. 93:131-135(1996).
- Scherer P.E., J. Biol. Chem. 272:29337-29346(1997).
- Engelman J.A., FEBS Lett. 448:221-230(1999).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Caveolin 2 (phospho Tyr27) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 27 (L-E-Y (p)-A-D) derived from Human Caveolin 2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
858
NCBI Official Name:
caveolin 2
NCBI Official Symbol:
CAV2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
NP_001224.1
Protein GI Number:
4557413
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Caveolin 2 only when phosphorylated at tyrosine 27.
Swissprot #:
P51636