Claudin 3 (phospho Tyr219) Antibody
| Code | Size | Price |
|---|
| PSI-79-901-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
CLD3, CLDN3, HRVP1, CPE-R 2, CPE-receptor 2
Application Note:
Western Blot: 1:500~1:1000
Background:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.
Background References:
- Peacock R.E., Genomics 46:443-449(1997).
- Katahira J., J. Biol. Chem. 272:26652-26658(1997).
- The MGC Project Team; Genome Res. 14:2121-2127(2004).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Claudin 3 (phospho Tyr219) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 219 (R-K-D-Y (p)-V) derived from Human Claudin 3.
Modifications:
Phospho-Specific
NCBI Gene ID #:
1365
NCBI Official Name:
claudin 3
NCBI Official Symbol:
CLDN3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
NP_001297.1
Protein GI Number:
6685273
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Claudin 3 only when phosphorylated at tyrosine 219.
Swissprot #:
O15551