HS1 (phospho Tyr397) Antibody
| Code | Size | Price |
|---|
| PSI-79-926-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
HCLS1, LCKBP1, Hematopoietic cell- specific LYN substrate 1
Application Note:
Western Blot: 1:500~1:1000
Background:
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression.
Background References:
- Kitamura D., Nucleic Acids Res. 17:9367-9379(1989).
- Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
- Ota T., Nat. Genet. 36:40-45(2004).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
HS1 (phospho Tyr397) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 397 (G-D-Y (p)-E-E) derived from Human HS1 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
3059
NCBI Official Name:
hematopoietic cell-specific Lyn substrate 1
NCBI Official Symbol:
HCLS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
NP_005326.2
Protein GI Number:
167234422
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of HS1 only when phosphorylated at tyrosine 397.
Swissprot #:
P14317