Adrenergic Receptor beta2 (phospho Ser346) Antibody

Contact us
ProSci
Product Code: PSI-80-019
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-80-019-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

1 / 1
Western blot analysis of extracts from HepG2 cells treated with Nocodazole using Phospho-Adrenergic Receptor beta2 (Ser346) Antibody. The lane on the right is treated with the antigen-specific peptide.
❮❯

Western blot analysis of extracts from HepG2 cells treated with Nocodazole using Phospho-Adrenergic Receptor beta2 (Ser346) Antibody. The lane on the right is treated with the antigen-specific peptide.

Documents

Further Information

Additional Names:
ADRB2R, B2AR, adrenergic receptor, beta-2,
Application Note:
Western Blot: 1:500~1:1000
Background:
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Background References:
  • Gao S, Malbon C, Wang HY (2014) J Mol Signal 9, 3
  • 24690384 Curated Info
  • Vistein R, Puthenveedu MA (2013) Proc Natl Acad Sci U S A 110, 15289-94
  • Gimenez LE, et al. (2012) J Biol Chem 287, 9028-40
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Adrenergic Receptor beta2 (phospho Ser346) antibody was raised against a peptide sequence around phosphorylation site of serine 346 (R-S-S (p)-L-K) derived from Human Adrenergic Receptor beta2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
154
NCBI Official Name:
adrenoceptor beta 2, surface
NCBI Official Symbol:
ADRB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
NP_000015.1
Protein GI Number:
4501969
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of Adrenergic Receptor beta2 only when phosphorylated at serine 346.
Swissprot #:
P07550