Histamine H1 Receptor (phospho Ser398) Antibody
Code | Size | Price |
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PSI-79-814-0.1mg | 0.1mg | £488.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Immunofluorescence (IF)
Storage:
Store antibody at -20°C for up to one year.
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Further Information
Additional Names:
H1-R, HRH1, histamine H1 receptor
Background:
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
Background References:
- de Backer M.D., Biochem. Biophys. Res. Commun. 197:1601-1608(1993).
- Fukui K., Biochem. Biophys. Res. Commun. 201:894-901(1994).
- Sjoeblom T., Science 314:268-274(2006)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Histamine H1 Receptor (phospho Ser398) antibody was raised against a peptide sequence around phosphorylation site of Serine 398 (S-H-S (p)-R-Q) derived from Human Histamine H1 Receptor .
Modifications:
Phospho-Specific
NCBI Gene ID #:
3269
NCBI Official Name:
histamine receptor H1
NCBI Official Symbol:
HRH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
NP_000852.1
Protein GI Number:
4504491
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Histamine H1 Receptor only when phosphorylated at serine 398.
Swissprot #:
P35367