HSF1 (phospho Thr142) Antibody
Code | Size | Price |
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PSI-79-830-0.1mg | 0.1mg | £488.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
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Further Information
Additional Names:
HSF 1, HSTF1, Heat shock factor protein 1
Background:
DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
Background References:
- Rabindran S.K., Proc. Natl. Acad. Sci. U.S.A. 88:6906-6910(1991).
- The MGC Project Team; Genome Res. 14:2121-2127(2004).
- Schuetz T.J.,Proc. Natl. Acad. Sci. U.S.A. 88:6911-6915(1991)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
HSF1 (phospho Thr142) antibody was raised against a peptide sequence around phosphorylation site of threonine 142 (L-L-T (p)-D-V) derived from Human HSF1 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
3297
NCBI Official Name:
heat shock transcription factor 1
NCBI Official Symbol:
HSF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
NP_005517.1
Protein GI Number:
5031767
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of HSF1 only when phosphorylated at threonine 142.
Swissprot #:
Q00613