iNOS (phospho Tyr151) Antibody
| Code | Size | Price |
|---|
| PSI-79-877-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
HEP-NOS, NOS2, inducible
Background:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Background References:
- Geller D.A., Proc. Natl. Acad. Sci. U.S.A. 90:3491-3495(1993).
- Sherman P.A., Biochemistry 32:11600-11605(1993).
- Charles I.G., Proc. Natl. Acad. Sci. U.S.A. 90:11419-11423(1993).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
iNOS (phospho Tyr151) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 151 (Q-Y-Y (p)-G-S) derived from Human iNOS .
Modifications:
Phospho-Specific
NCBI Gene ID #:
4843
NCBI Official Name:
nitric oxide synthase 2, inducible
NCBI Official Symbol:
NOS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
131 kDa
Protein Accession #:
NP_000616.3
Protein GI Number:
1352513
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Inos only when phosphorylated at tyrosine 151.
Swissprot #:
P35228