Girdin (phospho Ser1417) Antibody
| Code | Size | Price |
|---|
| PSI-79-914-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
APE, GIV, GRDN, HkRP1, KIAA1212
Background:
girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.
Background References:
- Enomoto A., Dev. Cell 9:389-402(2005).
- Simpson F., Traffic 6:442-458(2005).
- Hillier L.W., Nature 434:724-731(2005).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Girdin (phospho Ser1417) antibody was raised against a peptide sequence around phosphorylation site of Serine 417 (L-E-M (p)-A-Q) derived from Human Girdin .
Modifications:
Phospho-Specific
NCBI Gene ID #:
55704
NCBI Official Name:
coiled-coil domain containing 88A
NCBI Official Symbol:
CCDC88A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
216 kDa
Protein Accession #:
NP_060554.3
Protein GI Number:
50897852
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Girdin only when phosphorylated at serine 1417.
Swissprot #:
Q3V6T2