IL-2R beta/CD122 (phospho Tyr364) Antibody

ProSci
Product Code: PSI-79-816
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-816-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from COS7 cells using IL-2Rbeta/CD122 (Phospho-Tyr364) Antibody. The lane on the right is treated with the antigen-specific peptide.

Western blot analysis of extracts from COS7 cells using IL-2Rbeta/CD122 (Phospho-Tyr364) Antibody. The lane on the right is treated with the antigen-specific peptide.

Further Information

Additional Names:
CD122 antigen, P70-75, IL-2 receptor, IL-2R beta
Application Note:
Western Blot: 1:500~1:1000
Background:
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Background References:
  • Hatakeyama M., Science 244:551-556(1989).
  • Dunham I., Nature 402:489-495(1999).
  • Mulloy J.C., J. Virol. 70:3599-3605(1996)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IL-2R beta/CD122 (phospho Tyr364) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 364 (Q-G-Y (p)-F-F) derived from Human IL-2Rbeta/CD122 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
3560
NCBI Official Name:
interleukin 2 receptor, beta
NCBI Official Symbol:
IL2RB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
75 kDa
Protein Accession #:
NP_000869.1
Protein GI Number:
124321
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of IL-2Rbeta/CD122 only when phosphorylated at tyrosine 364.
Swissprot #:
P14784