HDAC7A (phospho Ser155) Antibody
Code | Size | Price |
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PSI-79-932-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
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Further Information
Additional Names:
HD7a, HDA7, HDAC7A
Application Note:
Western Blot: 1:500~1:1000
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Background References:
- Walsh M.J., Submitted (FEB-2000).
- Zelent A., Submitted (MAY-2003).
- Sugano S., Nat. Genet. 36:40-45(2004)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
HDAC7A (phospho Ser155) antibody was raised against a peptide sequence around phosphorylation site of Serine 155 (T-V-S (p)-E-P) derived from Human HDAC7A.
Modifications:
Phospho-Specific
NCBI Gene ID #:
51564
NCBI Official Name:
histone deacetylase 7
NCBI Official Symbol:
HDAC7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
103 kDa
Protein Accession #:
NP_056216.2
Protein GI Number:
30913097
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of HDAC7A only when phosphorylated at serine 155.
Swissprot #:
Q8WUI4