VAV3 (phospho Tyr173) Antibody
| Code | Size | Price |
|---|
| PSI-79-939-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
VAV3, FLJ40431, Guanine nucleotide exchange factor VAV3
Application Note:
Western Blot: 1:500~1:1000
Background:
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Background References:
- Trenkle T., Nucleic Acids Res. 26:3883-3891(1998).
- Movilla N., Mol. Cell. Biol. 19:7870-7885(1999).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
VAV3 (phospho Tyr173) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 173 (E-V-Y (p)-E-D) derived from Human VAV3.
Modifications:
Phospho-Specific
NCBI Gene ID #:
10451
NCBI Official Name:
vav 3 guanine nucleotide exchange factor
NCBI Official Symbol:
VAV3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
100 kDa
Protein Accession #:
NP_006104.4
Protein GI Number:
120432044
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of VAV3 only when phosphorylated at tyrosine 173.
Swissprot #:
Q9UKW4