Bcr (phospho Tyr360) Antibody

ProSci
Product Code: PSI-80-021
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-80-021-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from COS7 tissue using Bcr (Phospho-Tyr360) Antibody. The lane on the right is treated with the antigen-specific peptide.

Western blot analysis of extracts from COS7 tissue using Bcr (Phospho-Tyr360) Antibody. The lane on the right is treated with the antigen-specific peptide.

Further Information

Additional Names:
BCR, BCR protein, BCR1, Breakpoint cluster region protein,
Application Note:
Western Blot: 1:500~1:1000
Background:
GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.
Background References:
  • Perazzona B, et al. (2008) Oncogene 27, 2208-14. Sun T, Campbell M, Gordon W, Arlinghaus RB (2001) Biopolymers 60, 61-75 . Wu Y, Liu J, Arlinghaus RB (1998)Oncogene 16, 141-6.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Bcr (phospho Tyr360) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 360 (T-T-Y (p)-R-M) derived from Human Bcr.
Modifications:
Phospho-Specific
NCBI Gene ID #:
613
NCBI Official Name:
breakpoint cluster region
NCBI Official Symbol:
BCR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
142 kDa
Protein Accession #:
NP_004318.3
Protein GI Number:
82546843
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of Bcr only when phosphorylated at tyrosine 360.
Swissprot #:
P11274