SF1 (phospho Ser82) Antibody
| Code | Size | Price |
|---|
| PSI-79-794-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
BBP, CW17, SF01, ZFM1, ZNF162
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.
Background References:
- Susan Y. Park, Development, May 2005; 132: 2415 - 2423.
- Dujin Zhou, Mol. Endocrinol., Jul 2000; 14: 986.
- Dagmar Wilhelm, Genes & Dev., Jul 2002; 16: 1839.
- Philipp Gut,Development, Oct 2005; 132: 4611 - 4619.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SF1 (phospho Ser82) antibody was raised against a peptide sequence around phosphorylation site of Serine 82 (S-P-S (p)-P-E) derived from Human SF1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
7536
NCBI Official Name:
splicing factor 1
NCBI Official Symbol:
SF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
NP_004621.2
Protein GI Number:
42544130
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of SF1 only when phosphorylated at serine 82.
Swissprot #:
Q15637