Retinoblastoma (phospho Ser608) Antibody
Code | Size | Price |
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PSI-79-834-0.1mg | 0.1mg | £488.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
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Further Information
Additional Names:
P105-RB, PP105, PP110, RB1
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.
Background References:
- Lee W.-H., Nature 329:642-645(1987).
- Lee W.-H., Science 235:1394-1399(1987).
- Friend S.H., Proc. Natl. Acad. Sci. U.S.A. 84:9059-9063(1987).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Retinoblastoma (phospho Ser608) antibody was raised against a peptide sequence around phosphorylation site of Serine 608 (Y-L-S (p)-P-V) derived from Human Retinoblastoma.
Modifications:
Phospho-Specific
NCBI Gene ID #:
5925
NCBI Official Name:
retinoblastoma 1
NCBI Official Symbol:
RB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
NP_000312.2
Protein GI Number:
108773787
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Retinoblastoma only when phosphorylated at serine 608.
Swissprot #:
P06400