FRS2 (phospho Tyr436) Antibody
| Code | Size | Price |
|---|
| PSI-79-880-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
SNT-1, SNT2, FGFR signalling adaptor
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
FRS2 is an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways.
Background References:
- Xu H., J. Biol. Chem. 273:17987-17990(1998).
- Meakin S.O., J. Biol. Chem. 274:9861-9870(1999).
- Dhalluin C., Mol. Cell 6:921-929(2000).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
FRS2 (phospho Tyr436) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 436 (L-N-Y (p)-I-Q) derived from Human FRS2 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
10818
NCBI Official Name:
fibroblast growth factor receptor substrate 2
NCBI Official Symbol:
FRS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
NP_001036020.1
Protein GI Number:
110347408
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of FRS2 only when phosphorylated at tyrosine 436.
Swissprot #:
Q8WU20