WWOX (phospho Tyr33) Antibody
| Code | Size | Price |
|---|
| PSI-79-889-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
FOR, WOX1, Aberrant WW domain-containing oxidoreductase
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism.
Background References:
- Bednarek A.K., Cancer Res. 60:2140-2145(2000).
- Ried K., Hum. Mol. Genet. 9:1651-1663(2000).
- Bednarek A.K., Cancer Res. 61:8068-8073(2001).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
WWOX (phospho Tyr33) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 33 (W-V-Y (p)-Y-A) derived from Human WWOX.
Modifications:
Phospho-Specific
NCBI Gene ID #:
51741
NCBI Official Name:
WW domain containing oxidoreductase
NCBI Official Symbol:
WWOX
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
NP_057457.1
Protein GI Number:
7706523
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of WWOX only when phosphorylated at tyrosine 33.
Swissprot #:
Q96KM3