MEF2C (phospho Ser396) Antibody

ProSci
Product Code: PSI-79-917
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-917-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

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Western blot analysis of extracts from cos-7 cells (Lane 2), using MEF2C (Phospho-Ser396) Antibody. The lane on the left is treated with antigen-specific peptide.
2 / 2
Immunohistochemical analysis of paraffin-embedded human brain tissue using MEF2C (Phospho-Ser396) antibody (left) or the same antibody preincubated with blocking peptide (right).

Western blot analysis of extracts from cos-7 cells (Lane 2), using MEF2C (Phospho-Ser396) Antibody. The lane on the left is treated with antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human brain tissue using MEF2C (Phospho-Ser396) antibody (left) or the same antibody preincubated with blocking peptide (right).

Further Information

Additional Names:
Myocyte enhancer factor 2C, Myocyte-specific enhancer factor 2C, Similar to MADS box transcription enhancer factor 2 polypeptide C
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
MEF2C transcription factor of the MADS family which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. May be involved in myogenesis, neurogenesis and in the development of cortical architecture. Three splice-variant isoforms have been described.
Background References:
  • Leifer D., Proc. Natl. Acad. Sci. U.S.A. 90:1546-1550(1993).
  • McDermott J.C., Mol. Cell. Biol. 13:2564-2577(1993).
  • Wang A.H., Mol. Cell. Biol. 19:7816-7827(1999).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MEF2C (phospho Ser396) antibody was raised against a peptide sequence around phosphorylation site of Serine 396 (P-V-S (p)-P-P) derived from Human MEF2C.
Modifications:
Phospho-Specific
NCBI Gene ID #:
4208
NCBI Official Name:
myocyte enhancer factor 2C
NCBI Official Symbol:
MEF2C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
NP_001180279.1
Protein GI Number:
2500875
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of MEF2C only when phosphorylated at serine 396.
Swissprot #:
Q06413