ETS1 (phospho Thr38) Antibody

ProSci
Product Code: PSI-79-787
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-787-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.

Images

1 / 3
Western blot analysis of extracts from HepG2 cells using ETS1 (Phospho-Thr38) Antibody. The lane on the right is treated with the antigen-specific peptide.
2 / 3
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using ETS1 (Phospho-Thr38) antibody (left) or the same antibody preincubated with blocking peptide (right).
3 / 3

Western blot analysis of extracts from HepG2 cells using ETS1 (Phospho-Thr38) Antibody. The lane on the right is treated with the antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using ETS1 (Phospho-Thr38) antibody (left) or the same antibody preincubated with blocking peptide (right).

Further Information

Additional Names:
p54, ETS1, ETS-1, C-ets-1 protein
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Background:
Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.
Background References:
  • Tsukasa Higuchi, Mol. Cell. Biol., May 2007; 27: 3353 - 3366.
  • NK Bhat, PNAS, May 1990; 87: 3723.
  • H Suzuki, PNAS, May 1995; 92: 4442.
  • V Fafeur, Cell Growth Differ., Jun 1997; 8: 655.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ETS1 (phospho Thr38) antibody was raised against a peptide sequence around phosphorylation site of threonine 38 (L-L-T (p)-P-S) derived from Human ETS1 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
2113
NCBI Official Name:
v-ets avian erythroblastosis virus E26 oncogene homolog 1
NCBI Official Symbol:
ETS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
NP_035938.2
Protein GI Number:
4885219
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of ETS1 only when phosphorylated at threonine 38.
Swissprot #:
P27577