B-RAF (phospho Thr599) Antibody
| Code | Size | Price |
|---|
| PSI-79-804-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
B-RAF, RAFB1, RMIL, BRAF1, c-RMIL
Background:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron.
Background References:
- Armelle Calipel, J. Biol. Chem., Oct 2003; 278: 42409 - 42418.
- Tara J. Dillon, J. Biol. Chem., Sep 2003; 278: 35940 - 35949.
- R K Jaiswal, Mol. Cell. Biol., Oct 1994; 14: 6944 - 6953.
- Laura L. Dugan, J. Biol. Chem., Sep 1999; 274: 25842.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
B-RAF (phospho Thr599) antibody was raised against a peptide sequence around phosphorylation site of threonine 599 (L-A-T (p)-V-K) derived from Human B-RAF.
Modifications:
Phospho-Specific
NCBI Gene ID #:
673
NCBI Official Name:
v-raf murine sarcoma viral oncogene homolog B1
NCBI Official Symbol:
BRAF
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
NP_004324.2
Protein GI Number:
50403720
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of B-Raf only when phosphorylated at threonine 598.
Swissprot #:
P15056