Nuclear Receptor NR4A1 (phospho Ser351) Antibody
| Code | Size | Price |
|---|
| PSI-79-822-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
NGFIB, GFRP1, HMR, NR4A1, NAK1
Background:
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.
Background References:
- Nakai A., Mol. Endocrinol. 4:1438-1443(1990).
- Chang C., J. Steroid Biochem. 34:391-395(1989).
- Bondy G.P., Cell Growth Differ. 2:203-208(1991)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Nuclear Receptor NR4A1 (phospho Ser351) antibody was raised against a peptide sequence around phosphorylation site of Serine351 (L-P-S (p)-K-P) derived from Human Nuclear Receptor NR4A1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
3164
NCBI Official Name:
nuclear receptor subfamily 4, group A, member 1
NCBI Official Symbol:
NR4A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
64 kDa
Protein Accession #:
NP_002126.2
Protein GI Number:
27894346
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Nuclear Receptor NR4A1 only when phosphorylated at serine 351
Swissprot #:
P22736