PDK1 (phospho Tyr9) Antibody
| Code | Size | Price |
|---|
| PSI-79-833-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
hPDK1, PDPK1, mPDK1, PkB kinase
Background:
Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development.
Background References:
- Alessi D.R., Curr. Biol. 7:261-269(1997).
- Alessi D.R.,Curr. Biol. 7:776-789(1997).
- Stephens L.R.,Science 279:710-714(1998)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PDK1 (phospho Tyr9) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 9 (A-L-Y (p)-D-A) derived from Human PDK1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
5170
NCBI Official Name:
3-phosphoinositide dependent protein kinase-1
NCBI Official Symbol:
PDPK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
NP_002604.1
Protein GI Number:
4505695
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of PDK1 only when phosphorylated at tyrosine 9.
Swissprot #:
O15530