EPHA3/4/5 (phospho Tyr779/833) Antibody
| Code | Size | Price |
|---|
| PSI-79-843-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
EPA3, ETK, HEK, MEK4, REK
Background:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.
Background References:
- Wicks I.P., Proc. Natl. Acad. Sci. U.S.A. 89:1611-1615(1992).
- Chiari R., Cancer Res. 60:4855-4863(2000).
- Boyd A.W., J. Biol. Chem. 267:3262-3267(1992).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
EPHA3/4/5 (phospho Tyr779/833) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 779/833 (E-A-Y (p)-T-T)/ (Q-D-V (p)-I-K) derived from Human EPHA3/4/5.
Modifications:
Phospho-Specific
NCBI Gene ID #:
2042/2043
NCBI Official Name:
EPH receptor A3, EPH receptor A4
NCBI Official Symbol:
EPHA3, EPHA4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
NP_004429.1
Protein GI Number:
21361241
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of EPHA3/4/5 only when phosphorylated at tyrosine 779/833.
Swissprot #:
P29320/54764/54756