APLP2 (phospho Tyr755) Antibody
Code | Size | Price |
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PSI-79-894-0.1mg | 0.1mg | £488.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
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Further Information
Additional Names:
Amyloid protein homolog , Amyloid-like protein 2 precursor, APP2, APPH, CDEI-box binding protein
Background:
APLP2 May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box).
Background References:
- Sprecher C.A., Biochemistry 32:4481-4486(1993).
- Wasco W., Nat. Genet. 5:95-99(1993).
- von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
APLP2 (phospho Tyr755) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 755 (P-T-Y (p)-K-Y) derived from Human APLP2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
334
NCBI Official Name:
amyloid beta (A4) precursor-like protein 2
NCBI Official Symbol:
APLP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
86 kDa
Protein Accession #:
NP_001633.1
Protein GI Number:
214010181
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of APLP2 only when phosphorylated at tyrosine 755
Swissprot #:
Q06481