Claudin 5 (phospho Tyr217) Antibody
| Code | Size | Price |
|---|
| PSI-79-902-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20°C for up to one year.
Documents
Further Information
Additional Names:
CLD5, CLDN5, TMDVCF
Background:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.
Background References:
- Sirotkin H., Genomics 42:245-251(1997).
- Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).
- The MGC Project Team; Genome Res. 14:2121-2127(2004).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Claudin 5 (phospho Tyr217) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 217 (K-K-N-Y (p)-V) derived from Human Claudin 5.
Modifications:
Phospho-Specific
NCBI Gene ID #:
7122
NCBI Official Name:
claudin 5
NCBI Official Symbol:
CLDN5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
NP_001124333.1
Protein GI Number:
6685271
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Claudin 5 only when phosphorylated at tyrosine 217.
Swissprot #:
O00501